diff --git a/README.md b/README.md index bbcc8fa..ab479c4 100644 --- a/README.md +++ b/README.md @@ -1,5 +1,5 @@ -# PPLM: A Corporative Language Model for Protein-Protein Interaction, Binding Affinity, and Interface Contact Prediction +# PPLM: A Paired Sequence Language Model for Protein-Protein Interaction Modeling ![PPLM Pipeline](Pipeline.png) @@ -8,7 +8,7 @@ **Version 1.0, 03/25/2025** (Copyrighted by the Regents of the National University of Singapore, All rights reserved) -PPLM is a protein–protein language model that learns directly from paired sequences through a novel +PPLM is a protein–pair language model that learns directly from paired sequences through a novel attention architecture, explicitly capturing inter-protein context. Building on PPLM, we developed PPLM-PPI, PPLM-Affinity, and PPLM-Contact for predicting protein–protein interactions, estimating binding affinity, and identifying interface residue contacts, respectively.