diff --git a/preprocessing/pipelines.py b/preprocessing/pipelines.py
index cdbf61b..9d35af9 100644
--- a/preprocessing/pipelines.py
+++ b/preprocessing/pipelines.py
@@ -199,6 +199,7 @@ class Pipeline():
                 print('Saving processed dataset...')
                 t = time.time()
                 env = {'inputs': inputs, 'outputs': outputs,'failed_samples':failed_samples}
+                os.makedirs(os.path.dirname(location_processed_dataset),exist_ok=True)
                 io_utils.save_pickle(
                     env, location_processed_dataset)
                 print('Processed dataset saved (t=%.f s)' % (time.time() - t))
diff --git a/train.py b/train.py
index d40c6a6..c32467b 100644
--- a/train.py
+++ b/train.py
@@ -77,7 +77,7 @@ if __name__ == '__main__':
     '''
     check = False # Check = True to verify installation, =False for full training.
     train = True # True to retrain, False to evaluate the model shown in paper.
-    use_evolutionary = True # True to use evolutionary information (requires hhblits and a sequence database), False otherwise.
+    use_evolutionary = False # True to use evolutionary information (requires hhblits and a sequence database), False otherwise.
     Lmax_aa = 256 if check else 1024
     ''' 
     Maximum length of the protein sequences.
diff --git a/transfer_learning_train.py b/transfer_learning_train.py
index 90b42a5..6676522 100644
--- a/transfer_learning_train.py
+++ b/transfer_learning_train.py
@@ -21,7 +21,7 @@ if __name__ == '__main__':
     train = True # True to retrain, False to evaluate the model shown in paper.
     transfer = True # If False, retrain from scratch.
     freeze = False # If True, evaluate the binding site network without fine tuning.
-    use_evolutionary = True # True to use evolutionary information (requires hhblits and a sequence database), False otherwise.
+    use_evolutionary = False # True to use evolutionary information (requires hhblits and a sequence database), False otherwise.
     Lmax_aa = 256 if check else 2120
     ''' 
     Lmax_aa is the maximum length of the protein sequences.