From 6462d22ecf784e00984abb4448baf27708537ace Mon Sep 17 00:00:00 2001 From: Raktim Mitra Date: Sat, 28 Mar 2026 12:04:48 -0700 Subject: [PATCH] main readme updates --- models/rfd3/README.md | 16 +++++++++------- models/rfd3/docs/examples/atom23_design.md | 2 +- 2 files changed, 10 insertions(+), 8 deletions(-) diff --git a/models/rfd3/README.md b/models/rfd3/README.md index 0886afc..bdbf0dd 100644 --- a/models/rfd3/README.md +++ b/models/rfd3/README.md @@ -1,6 +1,6 @@ # De novo Design of Biomolecular Interactions with RFdiffusion3 -RFdiffusion3 (RFD3) is a diffusion method that can design protein structures +RFdiffusion3 (RFD3) is a diffusion method that can design biopolymer structures under complex constraints. This repository contains both the training and inference code, and @@ -62,6 +62,8 @@ For example, you can fix sequence and not structure (prediction-type task), fix For full details on how to specify inputs, see the [input specification documentation](./docs/input.md). You can also see `foundry/models/rfd3/configs/inference_engine/rfdiffusion3.yaml` for even more options. +Nucleic acid design, along with proteins, is also possible using RFD3 using the atom23 checkpoints. For full details see the [atom23 design documentation](./docs/examples/atom23_design.md) + ## Further example JSONs for different applications Additional examples are broken up by use case. If you have cloned the repository, matching `.json` files are in `foundry/models/rfd3/docs/examples` @@ -75,30 +77,30 @@ you will need to change the path in the `.json` file(s) before running. diff --git a/models/rfd3/docs/examples/atom23_design.md b/models/rfd3/docs/examples/atom23_design.md index f0f3f53..91f54eb 100644 --- a/models/rfd3/docs/examples/atom23_design.md +++ b/models/rfd3/docs/examples/atom23_design.md @@ -133,7 +133,7 @@ Used in: } } ``` -### Note: Most of the above jsons is not actually reading the `input` field. Kept as a dummy for the `inference3_engine`. +### Note: Most of the above jsons is not actually reading the `input` field. Kept as a dummy for the `inference_engine`. ## 4. Ligand-Conditioned Aptamer Design
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Small molecule binder design

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Small molecule binder design

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Protein binder design

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Protein binder design

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Nucleic acid binder design

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Nucleic acid binder design

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Enzyme design

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Enzyme design

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Symmetric design

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Symmetric design

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Multipolymer design

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Multipolymer design