From 8ebf50f2d2950db794b4158e4df1d3d258f487ba Mon Sep 17 00:00:00 2001
From: =?UTF-8?q?Maciej=20W=C3=B3jcikowski?=
 <mwojcikowski@users.noreply.github.com>
Date: Wed, 17 Feb 2021 14:22:20 +0100
Subject: [PATCH] Sanitize molecules when SMILES needs to be produced (#3818)

---
 rdkit/Chem/PandasTools.py | 3 ++-
 1 file changed, 2 insertions(+), 1 deletion(-)

diff --git a/rdkit/Chem/PandasTools.py b/rdkit/Chem/PandasTools.py
index 2f16923dd..6d2d9bfc8 100644
--- a/rdkit/Chem/PandasTools.py
+++ b/rdkit/Chem/PandasTools.py
@@ -469,8 +469,9 @@ def LoadSDF(filename, idName='ID', molColName='ROMol', includeFingerprints=False
     close = None  # don't close an open file that was passed in
   records = []
   indices = []
+  sanitize = bool(molColName is not None or smilesName is not None)
   for i, mol in enumerate(
-      Chem.ForwardSDMolSupplier(f, sanitize=(molColName is not None), removeHs=removeHs,
+      Chem.ForwardSDMolSupplier(f, sanitize=sanitize, removeHs=removeHs,
                                 strictParsing=strictParsing)):
     if mol is None:
       continue