Commit Graph

79 Commits

Author SHA1 Message Date
Greg Landrum
d7971cc40c Fixes #171 2013-12-06 06:54:31 +01:00
Greg Landrum
8503b49b75 add MolOps::get3DDistanceMat() 2013-12-01 07:57:20 +01:00
Greg Landrum
b60b26039c add bondTypes and associated tests for FragmentOnBonds() 2013-11-02 07:54:10 +01:00
Greg Landrum
05b3c95473 add docs 2013-10-30 05:25:38 +01:00
Greg Landrum
afb9f1ddfa add fragmentOnBonds() to python API
Fixes #142
2013-10-30 04:59:29 +01:00
Greg Landrum
73657cd33f add to python wrapper 2013-10-27 14:42:57 +01:00
Greg Landrum
2e1bb83ea0 add in-place form of mergeQueryHs() 2013-10-04 08:56:38 +02:00
Greg Landrum
6a6205cf9e Fixes #39 2013-06-02 06:18:43 +02:00
Greg Landrum
5b67e9c3e0 rename layered fingerprint2 -> pattern fingerprint
rearrange fingerprint code a bit
2013-03-28 09:44:33 +00:00
Greg Landrum
286d414b66 remove unused arguments for LayeredFingerprintMol 2013-03-28 03:56:00 +00:00
Sereina Riniker
589aad4fa2 update MolOps.cpp for older boost version 2013-03-27 12:44:04 +00:00
Greg Landrum
c96bb8dca2 forgot to remove a debug print 2013-03-12 04:40:50 +00:00
Greg Landrum
d1cae9346f an initial version of the "atomBits" feature for RDKit fingerprints 2013-03-12 04:39:43 +00:00
Greg Landrum
a304cbab16 expose fragmentOnBRICS bonds to python 2013-01-31 04:55:05 +00:00
Greg Landrum
03ef0e6f1b Add support for merging recursive queries on the C++ side
(contribution from Sereina Riniker)

A pure Python version of this was in the tutorial material from the RDKit UGM.
2013-01-08 15:13:01 +00:00
Greg Landrum
57572918de add initial support for addRecursiveQueries to ChemTransforms.
active and tested in C++ and python, in the SWIG wrapper but untested.
still needs linux and windows builds.
2012-12-17 09:06:02 +00:00
Greg Landrum
96760b37de fix and test sf.net issue 270 2012-12-04 07:13:08 +00:00
Greg Landrum
c9e55a65bf add fromAtoms support for fingerprints 2012-09-14 16:17:30 +00:00
Greg Landrum
93f6445e01 minor cleanup to RWMol::insertMol; add combineMols to ChemTransforms 2012-07-10 04:00:46 +00:00
Greg Landrum
d895c2108a the problem was actually on 32bit machines, not windows... update for that 2012-04-12 06:28:09 +00:00
Greg Landrum
40ecb362c1 get that working again on linux 2012-04-12 04:46:00 +00:00
Greg Landrum
6229f639a5 clean up some debugging printing; get the handling of the sanitization options more robust on windows; this needs testing back on mac and linux 2012-04-12 04:23:41 +00:00
Greg Landrum
f3d06ac331 refactor a bit to make this more logical 2012-03-26 03:08:02 +00:00
Greg Landrum
2bb34056dd first pass at adding support for atom invariants in the rdkit, atom-pairs, and topological torsions fingerprints 2012-03-25 12:58:42 +00:00
Greg Landrum
35a01ad00c doc updates 2012-02-26 18:53:19 +00:00
Greg Landrum
7ba9571e3c further refinements 2012-02-26 08:47:14 +00:00
Greg Landrum
39e986b775 updates to docs and release notes 2012-01-07 06:53:11 +00:00
Greg Landrum
3eeb1bf30c initial version of a DFS-based ring finder 2012-01-02 15:34:43 +00:00
Greg Landrum
ccbf50075b add another experimental version of the layered fingerprint (backup commit, this is not yet done) 2011-12-08 06:03:03 +00:00
Greg Landrum
92533d95d5 expose the Cleanup() function 2011-07-11 03:03:54 +00:00
Greg Landrum
f87a54950d documentation update 2011-04-02 04:58:48 +00:00
Greg Landrum
3ba11316b2 initial pass at requiring core-dummy matches in replaceCore; remove an extra header import from MolOps.cpp 2011-03-28 06:13:48 +00:00
Greg Landrum
d6741adc22 make some types more explicit in MolOps.h (easier SWIG wrapping)
support finding non-specfied chiral centers
remove vestigial GetFragmentSmiles() function
additional flexibility in AllChem.TransformMol()
2011-02-24 08:00:39 +00:00
Greg Landrum
e2521dccbc add murcko decomposition;
be sure pathToSubmol copies over coordinates
2011-02-21 06:43:53 +00:00
Greg Landrum
28747ea745 checkin some fragment and fingerprint changes. these are not yet well tested 2011-01-14 06:24:03 +00:00
Greg Landrum
3b3d44db16 remove exe property from source files 2011-01-13 04:22:56 +00:00
Greg Landrum
90787f08ad fix a core leak 2011-01-05 08:45:35 +00:00
Greg Landrum
7baa1769fd switch to having the RDKit fingerprinter default to 2 bits per path instead of 4 2011-01-02 11:17:15 +00:00
Greg Landrum
c25a2dde0f improve docstrings 2010-12-28 05:24:36 +00:00
Greg Landrum
c07c7220c7 more tuning of the substruct fingerprint 2010-11-22 04:12:00 +00:00
Greg Landrum
f3fbef45c5 update copyright statements 2010-09-26 17:04:37 +00:00
Greg Landrum
60894f6e22 make assignRadicals visible to client code 2010-09-20 02:09:24 +00:00
Greg Landrum
4b78f97572 add findAllPathsOfLengthsMtoN(), corresponds to findAllSubgraphsOfLengthsMtoN()
support path-based (i.e. non-branched fingerprints)
2010-08-21 00:20:18 +00:00
Greg Landrum
33121bd4f3 add FindAllSubgraphsofLengthMToN 2010-07-22 07:49:23 +00:00
Greg Landrum
7065810cfd - add describeQuery() method to atoms (this is primarily for debugging)
- add SetConjugation() and SetHybridization() methods for molecules.
2010-06-23 04:14:25 +00:00
Greg Landrum
c164209877 doc updates 2010-04-10 01:01:57 +00:00
Greg Landrum
27bcbc105c rework the way version names are exposed to python to replace leading and trailing __s with a single leading _ 2010-01-27 05:01:58 +00:00
Greg Landrum
22e60f20aa update versioning information 2010-01-26 05:29:25 +00:00
Greg Landrum
96adbc11ea remove the deprecated assign{Atom,Bond}ChiralCodes functions 2009-08-02 15:33:08 +00:00
Greg Landrum
bd738367e3 remove the function DaylightFingerprintMol() 2009-07-02 04:32:36 +00:00