105 Commits

Author SHA1 Message Date
Greg Landrum
159e36e5fd add support for including chirality in the AtomPairs and TopologicalTorsions descriptors 2013-04-07 23:39:30 +00:00
Greg Landrum
11e09f7d8b further fingerprint improvements;
remove unused arguments for the layered fingerprint
2013-03-28 03:54:13 +00:00
Greg Landrum
29e36be8b4 back to the original fp hashing scheme + atom degrees 2013-03-25 14:39:52 +00:00
Greg Landrum
e4798fa498 another pass at getting the path canonicalization working 2013-03-25 09:13:58 +00:00
Greg Landrum
b3aa7e0a4e new hashing algorithm for path-based fingerprints pass 1;
definitely some optimization work left to do, but this works and passes tests
2013-03-17 11:29:59 +00:00
Greg Landrum
d1cae9346f an initial version of the "atomBits" feature for RDKit fingerprints 2013-03-12 04:39:43 +00:00
Greg Landrum
357f41cc5f somewhat optimized version from Roger.
get the return vector the right size.
note: this still is not thread safe.
2013-02-10 04:18:19 +00:00
Greg Landrum
a597e0ac0a add C++ implementation of MACCS keys
(contribution from Roger Sayle)
2013-02-09 16:01:07 +00:00
Greg Landrum
2936cec6ff add fromAtoms support for RDKit and layered fingerprints 2012-09-13 04:34:43 +00:00
Greg Landrum
d84d5218a9 further layeredfp2 improvements 2012-07-09 05:19:33 +00:00
Greg Landrum
11c42cf1b2 fix an oversight: add getHashedMorganFingerprint 2012-07-02 07:03:55 +00:00
Greg Landrum
1c95a978dd fix a typo 2012-04-06 05:42:53 +00:00
Greg Landrum
2bb34056dd first pass at adding support for atom invariants in the rdkit, atom-pairs, and topological torsions fingerprints 2012-03-25 12:58:42 +00:00
Greg Landrum
6dcbdb246b at this point I think all descriptors and fingerprints work 2012-02-25 07:14:29 +00:00
Greg Landrum
a99ad44859 clean up some compiler warnings 2011-12-31 15:58:57 +00:00
Greg Landrum
561b41522a fix issue 3415636 2011-09-30 05:53:00 +00:00
Greg Landrum
dac565e485 add the ability to ignore atoms in the TT and AP fingerprints 2011-06-15 03:20:10 +00:00
Greg Landrum
28747ea745 checkin some fragment and fingerprint changes. these are not yet well tested 2011-01-14 06:24:03 +00:00
Greg Landrum
3b3d44db16 remove exe property from source files 2011-01-13 04:22:56 +00:00
Greg Landrum
7baa1769fd switch to having the RDKit fingerprinter default to 2 bits per path instead of 4 2011-01-02 11:17:15 +00:00
Greg Landrum
9301733e6c another round of query fingerprint improvement 2010-11-20 15:23:42 +00:00
Greg Landrum
f3fbef45c5 update copyright statements 2010-09-26 17:04:37 +00:00
Greg Landrum
ff7d14f692 include ring-membership by default in the morgan fps 2010-09-15 05:59:27 +00:00
Greg Landrum
6e31713dd9 correct handling of chirality and make it optional (now by default disabled);
allow bond order to be ignored
2010-09-04 05:54:27 +00:00
Greg Landrum
a25f17a45c add fcfp-like invariants for the morgan fingerprinter 2010-09-02 06:00:17 +00:00
Greg Landrum
4b78f97572 add findAllPathsOfLengthsMtoN(), corresponds to findAllSubgraphsOfLengthsMtoN()
support path-based (i.e. non-branched fingerprints)
2010-08-21 00:20:18 +00:00
Greg Landrum
c78be3f5ee another change to the hashing mechanism; version bump; query miss cleared up 2010-08-14 11:35:00 +00:00
Greg Landrum
8800620677 fix a problem with layered fingerprint hashing; switch back to using the RNG to generate bits 2010-07-27 19:56:54 +00:00
Greg Landrum
9c4870ba63 tests for issue 3030388 2010-07-17 05:40:33 +00:00
Greg Landrum
04dc23247e add additional forms of the morgan, atom-pair, and topological torsion fps 2010-07-02 04:17:21 +00:00
Greg Landrum
7d5a9f75ff move the AtomPair and TopologicalTorsion fingerprint code into the Fingerprints directory 2010-06-20 06:15:37 +00:00
Greg Landrum
3951d47b5f add option to get fingerprint as bit vector 2010-06-20 05:12:33 +00:00
Greg Landrum
20096c76a9 refactoring of the BitVect interface to make capitalization consistent
w/ the rest of the RDKit. i.e.: SetNumBits -> setNumBits
2010-05-30 15:15:46 +00:00
Greg Landrum
655ec54b16 fix and test issue 2875658 2009-10-10 06:05:24 +00:00
Greg Landrum
db4b9aaab4 handle sf.net issue 2848863 2009-09-02 03:50:34 +00:00
Greg Landrum
bd738367e3 remove the function DaylightFingerprintMol() 2009-07-02 04:32:36 +00:00
Greg Landrum
cde962ad6e support queries better in the layered fingerprinting 2009-05-07 13:29:54 +00:00
Greg Landrum
498dccf417 support more control over layered fps 2009-04-15 09:47:46 +00:00
Greg Landrum
c0759d094c fix a fromAtoms problem with the morgan fps 2009-03-06 09:17:12 +00:00
Greg Landrum
7f190d58b6 support doing Morgan fingerprints only from particular atoms 2009-03-05 12:52:34 +00:00
Greg Landrum
2485fa00f3 minor cleanup work 2009-03-05 10:16:16 +00:00
Greg Landrum
f7127675d9 add morgan fingerprints 2009-03-05 08:01:26 +00:00
Greg Landrum
e94b0090ae make the layered fingerprints more suited for substructure filtering 2009-02-10 10:17:22 +00:00
Greg Landrum
f98527e572 minor reorg 2008-12-11 07:29:23 +00:00
Greg Landrum
dc87df759a merge in layered fingerprints branch (https://rdkit.svn.sourceforge.net/svnroot/rdkit/branches/LayeredFingerprints_22Nov2008), revs 889:922 2008-12-11 04:55:08 +00:00
Greg Landrum
06736b4446 this now passes with boost 1.35 instead of 1.34.1; edit to get 1.34.1 compatibility back 2008-05-26 17:05:22 +00:00
Greg Landrum
830e96a231 remove a compiler warning 2008-05-20 06:51:47 +00:00
Greg Landrum
2f91b59836 do an explicit backwards compatibility check with fingerprints 2008-05-17 05:57:41 +00:00
Greg Landrum
f71a301574 rename the new fingerprint to RDKFingerprint instead of RDKFingerprint2 2008-05-08 18:44:45 +00:00
Greg Landrum
8f8a885b50 test required fp trends;some optimization work 2008-04-09 07:10:30 +00:00