Commit Graph

71 Commits

Author SHA1 Message Date
Greg Landrum
f48812238d Fixes #352 2014-10-20 05:23:38 +02:00
Greg Landrum
89729f8e2f Fixes #334 2014-09-17 21:52:13 +02:00
Greg Landrum
7fdac1f3a4 Fixes #295 2014-08-11 15:34:02 +02:00
Greg Landrum
7306903ef7 use boost::flyweight to ensure thread-safe construction of the pattern fingerprint queries 2014-05-08 04:27:06 +02:00
Greg Landrum
34ab68ca2a introduce QueryBond::QueryMatch, as with QueryAtoms;
all tests passing;
performance tests still needed
2014-05-07 05:29:25 +02:00
Greg Landrum
12a97b3bd2 fixes the bug, but probably drastically drops the screenout rate 2014-05-06 03:25:20 +02:00
Greg Landrum
9f11a37753 test multi-threaded use of the pattern fingerprint; this passes on the mac, but I am skeptical about it 2014-04-28 11:53:43 +02:00
Greg Landrum
40d19aad14 Fixes #251 2014-04-21 06:28:39 +02:00
Sereina Riniker
a0aece7204 option useCounts for Morgan fingerprints updated 2014-03-28 08:58:21 +01:00
Sereina Riniker
cc75d0d20d new option useCounts for Morgan fingerprints 2014-03-27 17:36:39 +01:00
Greg Landrum
9e1fb4d19a fix a typo causing problems with older vc++ versions 2014-02-25 05:19:55 +01:00
Greg Landrum
7ffd918143 Fixes #195 2014-01-16 01:52:58 -05:00
Greg Landrum
6dd83d03f6 Fixes #151 2013-11-10 06:50:10 +01:00
Greg Landrum
00d350c000 Fixes #151 2013-11-10 06:07:49 +01:00
Greg Landrum
99f90961d7 more help for gcc 4.1 2013-10-17 04:05:14 +02:00
Greg Landrum
2b91c62d23 githut 25 tests 2013-05-01 03:43:53 +00:00
Greg Landrum
159e36e5fd add support for including chirality in the AtomPairs and TopologicalTorsions descriptors 2013-04-07 23:39:30 +00:00
Greg Landrum
11e09f7d8b further fingerprint improvements;
remove unused arguments for the layered fingerprint
2013-03-28 03:54:13 +00:00
Greg Landrum
29e36be8b4 back to the original fp hashing scheme + atom degrees 2013-03-25 14:39:52 +00:00
Greg Landrum
e4798fa498 another pass at getting the path canonicalization working 2013-03-25 09:13:58 +00:00
Greg Landrum
b3aa7e0a4e new hashing algorithm for path-based fingerprints pass 1;
definitely some optimization work left to do, but this works and passes tests
2013-03-17 11:29:59 +00:00
Greg Landrum
d1cae9346f an initial version of the "atomBits" feature for RDKit fingerprints 2013-03-12 04:39:43 +00:00
Greg Landrum
357f41cc5f somewhat optimized version from Roger.
get the return vector the right size.
note: this still is not thread safe.
2013-02-10 04:18:19 +00:00
Greg Landrum
a597e0ac0a add C++ implementation of MACCS keys
(contribution from Roger Sayle)
2013-02-09 16:01:07 +00:00
Greg Landrum
2936cec6ff add fromAtoms support for RDKit and layered fingerprints 2012-09-13 04:34:43 +00:00
Greg Landrum
d84d5218a9 further layeredfp2 improvements 2012-07-09 05:19:33 +00:00
Greg Landrum
11c42cf1b2 fix an oversight: add getHashedMorganFingerprint 2012-07-02 07:03:55 +00:00
Greg Landrum
1c95a978dd fix a typo 2012-04-06 05:42:53 +00:00
Greg Landrum
2bb34056dd first pass at adding support for atom invariants in the rdkit, atom-pairs, and topological torsions fingerprints 2012-03-25 12:58:42 +00:00
Greg Landrum
6dcbdb246b at this point I think all descriptors and fingerprints work 2012-02-25 07:14:29 +00:00
Greg Landrum
a99ad44859 clean up some compiler warnings 2011-12-31 15:58:57 +00:00
Greg Landrum
561b41522a fix issue 3415636 2011-09-30 05:53:00 +00:00
Greg Landrum
dac565e485 add the ability to ignore atoms in the TT and AP fingerprints 2011-06-15 03:20:10 +00:00
Greg Landrum
28747ea745 checkin some fragment and fingerprint changes. these are not yet well tested 2011-01-14 06:24:03 +00:00
Greg Landrum
3b3d44db16 remove exe property from source files 2011-01-13 04:22:56 +00:00
Greg Landrum
7baa1769fd switch to having the RDKit fingerprinter default to 2 bits per path instead of 4 2011-01-02 11:17:15 +00:00
Greg Landrum
9301733e6c another round of query fingerprint improvement 2010-11-20 15:23:42 +00:00
Greg Landrum
f3fbef45c5 update copyright statements 2010-09-26 17:04:37 +00:00
Greg Landrum
ff7d14f692 include ring-membership by default in the morgan fps 2010-09-15 05:59:27 +00:00
Greg Landrum
6e31713dd9 correct handling of chirality and make it optional (now by default disabled);
allow bond order to be ignored
2010-09-04 05:54:27 +00:00
Greg Landrum
a25f17a45c add fcfp-like invariants for the morgan fingerprinter 2010-09-02 06:00:17 +00:00
Greg Landrum
4b78f97572 add findAllPathsOfLengthsMtoN(), corresponds to findAllSubgraphsOfLengthsMtoN()
support path-based (i.e. non-branched fingerprints)
2010-08-21 00:20:18 +00:00
Greg Landrum
c78be3f5ee another change to the hashing mechanism; version bump; query miss cleared up 2010-08-14 11:35:00 +00:00
Greg Landrum
8800620677 fix a problem with layered fingerprint hashing; switch back to using the RNG to generate bits 2010-07-27 19:56:54 +00:00
Greg Landrum
9c4870ba63 tests for issue 3030388 2010-07-17 05:40:33 +00:00
Greg Landrum
04dc23247e add additional forms of the morgan, atom-pair, and topological torsion fps 2010-07-02 04:17:21 +00:00
Greg Landrum
7d5a9f75ff move the AtomPair and TopologicalTorsion fingerprint code into the Fingerprints directory 2010-06-20 06:15:37 +00:00
Greg Landrum
3951d47b5f add option to get fingerprint as bit vector 2010-06-20 05:12:33 +00:00
Greg Landrum
20096c76a9 refactoring of the BitVect interface to make capitalization consistent
w/ the rest of the RDKit. i.e.: SetNumBits -> setNumBits
2010-05-30 15:15:46 +00:00
Greg Landrum
655ec54b16 fix and test issue 2875658 2009-10-10 06:05:24 +00:00