Commit Graph

17 Commits

Author SHA1 Message Date
Greg Landrum
3ba11316b2 initial pass at requiring core-dummy matches in replaceCore; remove an extra header import from MolOps.cpp 2011-03-28 06:13:48 +00:00
Greg Landrum
633be739b0 - fix an edge case with disconnected molecules in the MurckoDecompose code.
- test that empty results are handled properly in MurckoDecompose.
2011-03-04 06:37:26 +00:00
Greg Landrum
e1e1e5929d fix assignment of dummy positions in replaceCore 2011-03-03 05:02:13 +00:00
Greg Landrum
d6741adc22 make some types more explicit in MolOps.h (easier SWIG wrapping)
support finding non-specfied chiral centers
remove vestigial GetFragmentSmiles() function
additional flexibility in AllChem.TransformMol()
2011-02-24 08:00:39 +00:00
Greg Landrum
4ca59a1987 clean up conformer handling in ChemTransforms 2011-02-22 06:16:23 +00:00
Greg Landrum
e2521dccbc add murcko decomposition;
be sure pathToSubmol copies over coordinates
2011-02-21 06:43:53 +00:00
Greg Landrum
f3fbef45c5 update copyright statements 2010-09-26 17:04:37 +00:00
Greg Landrum
2805355f34 First pass at the rewrite:
this gets rid of all the "preceding atom" code and passes all tests on linux

builds on other OS's and more extensive regression testing is required
2010-05-31 14:08:11 +00:00
Greg Landrum
57cd641e50 in replaceCore: support labelling dummies with the index of the corresponding atom in the core 2008-11-06 09:10:38 +00:00
Greg Landrum
b36e6a911f fix a drawing bug
update release notes and docs
implement the new dummy atom stuff in ChemTransforms
expose lists of atom rings and bond rings from RingInfo
2008-05-14 20:20:52 +00:00
Greg Landrum
1d40302dcb This builds and tests correctly with msvc8. Linux and msvc7 tests are still required.
The primary changes consist of cleaning up edge cases that lead to memory errors (under VC8 with debugging turned out)
2008-02-16 05:25:53 +00:00
Greg Landrum
5b550374cb fix problems with chirality and replaceCore 2008-01-30 15:39:46 +00:00
Greg Landrum
a788e29511 merge the changes from the CanonicalizerRework30Nov branch in.
The changes are revs 451:498.
2008-01-30 14:53:04 +00:00
Greg Landrum
3e6cb74075 cleanup and documentation changes 2007-11-14 06:09:52 +00:00
Greg Landrum
5da5c9f7a6 add support for not removing dummies out from the core 2007-10-24 16:36:17 +00:00
Greg Landrum
9fb74bee78 this is not done yet 2007-07-31 16:53:08 +00:00
Greg Landrum
a890611a22 merge back in changes from ChemTransforms (r30:51);
the makefile for linux is still missing (I have one, I just need to retrieve it)
but otherwise this is in pretty good shape. 
err, I think so at least.
2006-09-15 16:44:38 +00:00