Commit Graph

40 Commits

Author SHA1 Message Date
Greg Landrum
6e2508972c all tests passing 2012-04-21 05:37:34 +00:00
Greg Landrum
e7d25d7973 tests passing except reactions 2012-04-21 04:40:55 +00:00
Greg Landrum
de2126b641 optimization work 2012-04-15 06:19:22 +00:00
Greg Landrum
dd609388e4 further improvements to getReactingAtoms() 2012-01-19 08:43:57 +00:00
Greg Landrum
e8cb290f18 add an initial pass at getReactingAtoms() for reactions 2012-01-18 05:52:38 +00:00
Greg Landrum
a99ad44859 clean up some compiler warnings 2011-12-31 15:58:57 +00:00
Greg Landrum
5e49aacd06 fix and test issue 3434271 2011-11-07 05:08:35 +00:00
Greg Landrum
2bc9481be8 further work on the SMARTS parser: support [13] as a free-standing query and update the reaction code so that the resulting queries work correctly in reactions 2011-10-29 05:51:05 +00:00
Greg Landrum
faab610321 add string replacements to smiles and smarts parsers 2011-05-22 10:45:14 +00:00
Greg Landrum
2ffaa92cf7 fix and test issue3228150;
note that as part of these changes MolToSmiles and MolToSmarts no longer have
side effects on the original molecule.
2011-03-26 06:51:50 +00:00
Greg Landrum
2cea8b58b4 fix for issue 3140490 2010-12-20 05:00:23 +00:00
Greg Landrum
18a8be8538 add isMoleculeReactantOfReaction() and isMoleculeProductOfReaction() convenience functions 2010-08-21 00:16:02 +00:00
Greg Landrum
5ef1a2c6eb improve depiction quality by (optionally) doing a bit of chemistry perception 2010-06-23 04:07:23 +00:00
Greg Landrum
46bfbba903 make sure to convert atoms from rxn files into queries;
add reaction depiction;
add ChemicalReactionToRxnBlock();
This stuff needs more testing and so far has only been built on linux.
2010-06-17 05:57:18 +00:00
Greg Landrum
fbf3e51f07 add ability to write reactions as SMARTS; RXN files still need to be done 2010-06-07 04:26:19 +00:00
Greg Landrum
a09fd9f63a cleanup work on file parsers code; add v3K rxn support 2010-06-03 06:59:48 +00:00
Greg Landrum
bf4e28e67c Change handling of atom-map numbers in SMARTS parsing.
this fixes sf.net bug 1804420
2010-01-15 06:41:16 +00:00
Greg Landrum
1896aac566 transfer conformer data to products in reactions; sf.net issue 2832951 2009-08-06 04:39:04 +00:00
Greg Landrum
cefd866c37 the implicit property stuff should be "private";
allow extraction of the reaction/product template molecules
2009-06-02 06:47:52 +00:00
Greg Landrum
7fdece9cd7 initial pass at supporting reaction pickles 2009-06-02 05:06:06 +00:00
Greg Landrum
527a3ccc6a handle dots in reactions correctly; this needs a bug entered against it. 2009-03-17 16:40:22 +00:00
Greg Landrum
82661fb59b partial fix for sf.net issue 2540021;
valence changes caused by modifying bond orders still not handled
2009-02-02 05:30:26 +00:00
Greg Landrum
e1a4c98503 enforce reaction initialization requirement 2008-11-26 10:44:56 +00:00
Greg Landrum
1e5f0afcf6 fix handling of properties in the products 2008-11-26 07:41:33 +00:00
Greg Landrum
de86e06e10 make sure aromaticity flags get copied onto dummy atoms too 2008-11-17 14:33:52 +00:00
Greg Landrum
110e67c1a0 support query bonds in the products 2008-11-17 14:00:27 +00:00
Greg Landrum
023f7b4f0f Merge changes from the iterative chirality branch:
https://rdkit.svn.sourceforge.net/svnroot/rdkit/branches/IterativeChirality_20Aug2008
into the trunk.
This covers revs 798-828.

Dependent chirality should now be correctly handled, but the
handling of ring stereochemistry, i.e. things like:
C[C@H]1CC[C@H](C)CC1
is still not 100% correct.
2008-09-19 09:40:15 +00:00
Greg Landrum
335d379d35 fix and test issue 2050085 2008-08-14 11:49:19 +00:00
Greg Landrum
7b1d76a295 Should have been part of previous commit. 2008-08-13 04:57:32 +00:00
Greg Landrum
f5b0d637aa don't update implicit props when the atomic number changes 2008-04-25 05:04:05 +00:00
Greg Landrum
b1aac14542 progress towards fixing and testing issue 1934052 2008-04-24 05:41:03 +00:00
Greg Landrum
e28938475f a couple more chirality tests for reactions 2008-04-08 10:22:19 +00:00
Greg Landrum
31d03cc949 further progress towards fixing bug 1920627 2008-04-01 19:34:27 +00:00
Greg Landrum
45ad82f715 further tests of sf.net Issue 1920627 2008-03-26 05:20:01 +00:00
Greg Landrum
84a48a03c7 preliminary fix for sf.net issue 1920627
more testing is required, but this should have it mostly solved
2008-03-25 06:36:59 +00:00
Greg Landrum
eebff68d3c test commit 2008-02-13 11:03:31 +00:00
Greg Landrum
e21af3db7b update chirality handling in reactions;
fix and test issue 1882479
make sure reaction tests get run when the GraphMol tests go;
2008-01-31 06:47:53 +00:00
Greg Landrum
38e5d9d030 fix stupid typo in the copyright
add test for sf.net bug 1804420
2007-09-29 06:34:30 +00:00
Greg Landrum
ebb196b8f8 Major thing here: fix and test Issue 1748846 (https://sourceforge.net/tracker/?func=detail&atid=814650&aid=1748846&group_id=160139)
Others:
SmilesParse: clean up some of the smiles generation code
2007-07-06 17:31:58 +00:00
Greg Landrum
80c76c59ac merge in chemical reactions branch (r173:183) 2007-02-23 18:05:50 +00:00